Table 1.
Animal's characteristics
| 8 weeks | 11 weeks | 14 weeks | ||||
|---|---|---|---|---|---|---|
| lean | fa/fa | lean | fa/fa | lean | fa/fa | |
| Body weight (g) | 207 ± 7 | 228 ± 6a | 298 ± 4 | 360 ± 4a | 314 ± 6 | 365 ± 9a |
| Liver (% body weight) | ND | ND | 3.31 ± 0.05 | 4.73 ± 0.09a | 3.23 ± 0.05 | 4.92 ± 0.10a |
| Gastrocnemius (% body weight) | ND | ND | 0.47 ± 0.01 | 0.28 ± 0.01a | 0.45 ± 0.01 | 0.27 ± 0.01a |
| Abdominal adipose tissue (% body weight) | ND | ND | 1.28 ± 0.06 | 3.54 ± 0.09a | 1.46 ± 0.04 | 3.87 ± 0.11a |
| Food intake (g/day) | ND | ND | 18.5 ± 1.5 | 37 ± 8a | 18.7 ± 1.2 | 34 ± 5a |
| Blood glucose (mg dL−1) | 115 ± 3 | 136 ± 9 | 111 ± 3 | 480 ± 19a | 112 ± 3 | 479 ± 19a |
| HbA1C (%) | 4.1 ± 0.03 | 4.2 ± 0.09 | 4.12 ± 0.06 | 8.86 ± 0.6a | 4.16 ± 0.1 | 10.76 ± 0.6a |
| Insulin (ng mL−1) | ND | ND | 1.32 ± 0.15 | 4.54 ± 0.76a | 1.68 ± 0.24 | 4.18 ± 0.57a |
Data are presented as mean ± SEM (n = 6). ND, not determined.
a
Significantly different than lean (P < 0.05) in each row.