Skip to main content
. 2015 Nov 18;4:e10935. doi: 10.7554/eLife.10935

Figure 2. Proposed mechanism for using ligands to hinder the aggregation of immunoglobulin VL s into amyloid fibrils.

Figure 2.

VL s are in equilibrium between dimers and monomers in solution. Ligands may be used to stabilize the VL dimer and therefore shift the equilibrium away from amyloid-prone monomers.

DOI: http://dx.doi.org/10.7554/eLife.10935.004