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. Author manuscript; available in PMC: 2016 Feb 19.
Published in final edited form as: Phys Med Biol. 2015 Sep 9;60(18):7309–7338. doi: 10.1088/0031-9155/60/18/7309

Table A1.

Glossary of variables used in the calculations. All times in ns. All distances in cm.

a Fraction of light received by a photodetector when the interaction point is at the same end of the scintillator and the opposite end is absorbing (equations (1a) and (1b))
c Speed of light in a vacuum (29.979 cm ns−1)
DAk Optical photon time dispersion parameter from photons emitted at depth Zk and either absorbed at rear surface B after being reflected at entrance surface A (equation (8b)), or absorbed directly at entrance surface A (equations (6a) and (9a))
DBk Optical photon time dispersion parameter from photons emitted at depth Zk and either absorbed at entrance surface A after being reflected at rear surface B (equation (6b)) or absorbed directly at rear surface B (equations (8a) and (9b))
d1 Constant coefficient for optical photon time dispersion (equations (2a) and (2b))
d2 Quadratic coefficient for optical photon time dispersion (equations (2a) and (2b))
δAjn Trigger delay from the arrival of the first possible photon at photodetector A (from an interaction at Zj) to the trigger time TAkn.
δBjn Trigger delay from the arrival of the first possible photon at photodetector B (from an interaction at Zj) to the trigger time TBkn.
EAkn Estimate of the entrance time of the annihilation photon using TAkn and correcting for the depth-dependent annihilation photon, optical photon, and trigger delays (equation (11a)) (should be zero with perfect timing)
EBkn Estimate of the entrance time of the annihilation photon using TBkn and correcting for the depth-dependent annihilation photon, optical photon, and trigger delays (equation (11b)) (should be zero with perfect timing)
EABkn Simple average of the corrected entrance times EAkn and EBkn for double-ended read-out (equation (12))
EWABkn Inverse-variance weighted average of EAkn and EBkn (equation (13))
fA(Z) Fraction of photons that reach surface A directly from an ionization event at depth Z (equation (1a))
fB(Z) Fraction of photons that reach surface B directly from an ionization event at depth Z (equation (1b))
Fn Fractional trigger level (tabulated from 0 to 1 on index n)
Fopt Fractional trigger level for minimum CRT (fraction of peak amplitude P) (figure B1)
H Number of photoelectrons contributing to the photodetector output pulse at the trigger time (table B1)
J Single photoelectron time jitter of the photodetector (Gaussian fwhm)
L Length of scintillator (distance between surfaces A and B)
μ Attenuation length for 511 keV annihilation photons in the scintillator
mAk Observed number of photoelectrons in photodetector A from an interaction at depth Zk (randomly distributed with mean = NAk, variance = NAk) (equation (4a))
mBk Observed number of photoelectrons in photodetector B from an interaction at depth Zk (randomly distributed with mean = NBk, variance = NBk) (equation (4b))
n Index of refraction of the scintillator at the wavelength of the scintillation light
Ng Number of ionization events used in each Monte Carlo calculation
Npe Number of photoelectrons produced in the photodetector (single-ended readout) or the sum in both photodetectors (double-ended readout). This is the product of the scintillator luminosity (photons/MeV), the energy deposited (511 keV), the photon transport efficiency, the photodetector fill factor, and the photodetector quantum efficiency.
NAk Expected number of photoelectrons in photodetector A for an interaction at depth Zk (equation (3a)).
NBk Expected number of photoelectrons in photodetector B for an interaction at depth Zk (equation (3b)).
PAk(max) Maximum amplitude of the photodetector A output pulse for interaction k
PBk(max) Maximum amplitude of the photodetector B output pulse for interaction k
P(t) Photodetector output pulse amplitude at time t summed over all earlier photoelectron responses (equation (7))
Rm Random number from a set uniformly distributed between 0 and 1
S(t) Photodetector SER (equation (5))
Sr Rise time of SER bi-exponential (equation (5))
Sd Decay time of SER bi-exponential (equation (5))
τd Decay time of the scintillator
τr Rise time of the scintillator
TAkn Trigger time of photodetector A for interaction k at trigger level Fn PAk(max) (sections 4.2.7, 4.3.7, and 4.4.7)
TBkn Trigger time of photodetector B for interaction k at trigger level Fn PBk(max) (sections 4.2.7, 4.3.7, and 4.4.7)
TABkn Simple average of TAkn and TBkn for double-ended readout. This corrects for the depth-dependent variation in optical photon delay but does not correct for the variations in annihilation photon or trigger delay. (section 4.4.8)
Tm Creation time of the photodetector output pulse from photoelectron m after the arrival of the annihilation photon at the entrance surface (sections 4.2.5, 4.3.5, 4.4.5).
VAjn Variance in the corrected trigger times EAkn averaged over bands of Zj
VBjn Variance in the corrected trigger times EBkn averaged over bands of Zj
WSA CRT for single-sided readout with the photodetector at surface A. Calculated as 1.4142 times the fwhm of the distribution of TAkn at the optimal trigger fraction (section 4.2.8).
WSB CRT for single-sided readout with the photodetector at surface B. Calculated as 1.4142 times the fwhm of the distribution of TBkn at the optimal trigger fraction.
WDAB CRT for double-ended readout using a simple average of the TAkn and TBkn for each interaction k and trigger fraction Fn. Calculated as 1.4142 times the fwhm of the distribution of TABkn at the optimal trigger fraction (section 4.4.13).
WEA CRT for double-ended readout using the optimal trigger time of only photodetector A but correcting for the estimated depth of the distribution of entrance time estimates. Calculated as 1.4142 times the fwhm of the distribution of EAkn at the optimal trigger fraction (section 4.4.13) (should be zero with perfect timing).
WEB CRT for double-ended readout using the optimal trigger time of only photodetector B but correcting for the estimated depth of the distribution of entrance time estimates. Calculated as 1.4142 times the fwhm of the distribution of EBkn at the optimal trigger fraction (section 4.4.13) (should be zero with perfect timing).
WEAB CRT for double-ended readout using a simple average of EAkn and EBkn. Calculated as 1.4142 times the fwhm of the distribution of EABkn at the optimal trigger fraction (section 4.4.13).
WWAB CRT for double-ended readout using the inverse weighted average of EAkn and EBkn. Calculated as 1.4142 times the fwhm of the distribution of EWABkn at the optimal trigger fraction (section 4.4.13).
WZ fwhm of the distribution of differences between Monte Carlo depth Z and estimated depth (section 4.4.15)
Zk Depth of interaction for interaction k. Randomly distributed according to exponential attenuation (section 4.1.1)
Depth of interaction estimated from observed photodetector photoelectron counts mAk and mBk (equation (10))