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. Author manuscript; available in PMC: 2016 Apr 1.
Published in final edited form as: Drug Discov Today Dis Models. 2014 May 9;15:37–41. doi: 10.1016/j.ddmod.2014.02.006

Figure 1.

Figure 1

Design space for treatment development. The identities, dosing schedules, and concentrations of multiple antibiotics can be varied. Similarly, the drugs, dosing schedules, and concentrations of multiple immune-modulators can be varied. Only 3 such parameters are shown. White arrows indicate movement between treatment outcomes as parameters are varied.