Table 7. Nominal logistic fits for three dependent variables (diagnosis, heredity and psychotic ever).
| Dependent variables → |
Bipolar|control |
Bipolar heredity (Y|N) |
Psychotic ever (Y|N) |
|||
|---|---|---|---|---|---|---|
| Independent variables ↓ | χ2 | P | χ2 | P | χ2 | P |
| logPKC_esc | 12.24 | 0.0005 | 7.62 | 0.0058 | 2.19 | 0.14 |
| ANK3 (CC, CT) | 3.21 | 0.073 | 4.30 | 0.038 | 2.04 | 0.15 |
| logPKC × ANK3 | 1.19 | 0.28 | 0.04 | 0.84 | 0.07 | 0.79 |
| Overall R2 | 0.15 | 0.14 | 0.05 | |||
| n | 73 | 73 | 71 | |||
| P= | 0.0016 | 0.0067 | 0.21 | |||
| Classification χ2 | 8.48 | 8.24 | 0.00 | |||
| P= | 0.0036 | 0.0041 | 0.98 | |||
| Sensitivity | 70% | 70% | 40% | |||
| Specificity | 67% | 79% | 71% | |||
Independent variables: escitalopram-stimulated protein kinase C activity (logPKC_esc) and the ANK3 (rs10761482) genotype. Simple effects are additive; no significant interactions were detected. Numbers in bold denote significant probabilities (P<0.05).