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Cellular concentrations of succinate in SK-N-BE(2) cells incubated with DMSO or DMS for 48 h in comparison to fumarate levels in cells incubated with DEF
The values are means ± S.D. of 3 independent assays.
| Cells treated | Unit | Succinate |
Fumarate cellular | |
|---|---|---|---|---|
| Nuclear | Cytosolic | |||
| DMSO | % of DMSO treated | 100 ± 10 | 100 ± 5 | 100a |
| 5 mm DMS | % of DMSO treated | 285 ± 65** | 255 ± 15*** | NDb |
| 40 μm DEF | % of DMSO treated | ND | ND | 180a |
a In HEK293 cells incubated for 20 h (24).
b ND, not determined.
