Skip to main content
. 2016 Feb 18;12(2):e1005867. doi: 10.1371/journal.pgen.1005867

Fig 4. Myc overexpression is sufficient to induce cytoophidia formation in Stage 10b follicle cells.

Fig 4

(A-E) In this stage-10b egg chamber, non-clonal cells (cells that are lack of GFP in B) have low levels of Myc (D) and only have very short cytoophidia, as indicated by an antibody against CTPsyn (C). UAS-Myc overexpression clones (i.e. Myc overexpression) marked with GFP (B, outlined in yellow in A-E) have increased levels of Myc (D) and much longer cytoophidia than non-clonal (nc, i.e. non-green) cells (C). DNA staining show that the nuclei in clones (green cells in E) are larger than those of nc cells (non-green cells in D). (F) Quantification shows that cytoophidia in Myc overexpression (UAS-Myc) cells are significantly increased in length, compared to those in nc cells. ***P<0.001. Error bars show SEM.