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. 2016 Jan 12;20(3):495–505. doi: 10.1111/jcmm.12754

Figure 5.

Figure 5

Involvement of Apelin‐13 in miR‐503‐mediated promotion of CF proliferation. (A and B) Apelin‐13 (100 nmol/l) decreased the expression of collagen I and collagen III in CFs transfected with miR‐503. (C and D) Apelin‐13 inhibited the expression of transforming growth factor‐β (TGF‐β) at the protein and mRNA levels in CFs transfected with miR‐503. (E and F) Apelin‐13 inhibited the expression of CTGF, a molecule downsteam of TGF‐β, at the protein and mRNA levels in CFs transfected with miR‐503. Data are expressed as the means ± S.E.M.; n = 5–6. *P < 0.05 versus control (no treatment); #P < 0.05 versus miR‐503.