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. 2016 Jan 12;20(3):506–517. doi: 10.1111/jcmm.12756

Figure 1.

Figure 1

Level of progranulin (PGRN) was increased in wild‐type (WT) mice after lipopolysaccharide (LPS) injection. (A) Serum levels of progranulin (PGRN). (B) Real‐time RT‐PCR analysis of relative PGRN mRNA level in mouse lung. (C) Representative western blot gel documents and summarized data showing the PGRN protein level in mouse lung. (D) ELISA of level of PGRN in homogenates in mouse lung. (E) Representative photomicrographs of immunohistochemical staining of mouse lung tissue using antibody to PGRN or negative control IgG. Data are mean ± S.D. *P < 0.05; **P < 0.01; ***P < 0.001 compared with control WT mice without LPS injection (Ctr) (n = 6 mice/group).