Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
PGRN deficiency decreased the survival of mice after LPS injection. WT and Grn −/− mice were subjected to endotoxic shock induced by injection of LPS at 50 (A), 35 (B), 25 (C), 10 (D), 5 (E), or 2.5 mg/kg (E); survival was monitored 3 times/day for 5 days. *P < 0.05; **P < 0.01; ***P < 0.001 compared with WT mice injected with LPS (n = 6 mice/group).
