Fig. 3. (a) Overlay of the X-ray crystal structures of fragments 1 (green) and 2 (blue), which together span the entire length of the EthR binding cavity and bind in four distinct sub-pockets denoted I, II, III and IV; (b–d) molecular structures 3, 4 and 5 arising from the merging of two adjacent overlapping fragment units of 1 and 2 bound to EthR.
