Fig. 8. Synthetic scheme for the preparation of 3-(1-(4-cyanophenyl)piperidin-4-yl)-N-(3-(piperidin-1-yl)phenyl)propanamide (23). (a) DCM, DIPEA, COMU, 22 °C; (b) TFA, DCM, 22 °C; 2 h; (c) 4-fluorobenzonitrile, K2CO3, anhydrous DMSO, 100 °C; 3 h.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.