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. 2016 Feb 19;6:21541. doi: 10.1038/srep21541

Table 3. Meta-regression and stratified analysis of pooled hazard ratios of R1 resection for disease-free survival.

Stratified analysis No. of studies No. of patients Pooled HR (95% CI) Heterogeneity Meta-regression
Fixed Random I2 p-value Residual I2 p-value
Overall 12 1905 1.567 (1.246–1.969) 1.596 (1.128–2.258) 37.5% 0.091*    
Adjuvant imatinib treatment             34.47% 0.252
Yes 5 717 1.193 (0.784–1.815) 1.308 (0.583–2.935) 53.2% 0.074*    
No 7 1188 1.758 (1.338–2.310) 1.785 (1.298–2.456) 11.3% 0.343    
Sample size             40.36% 0.523
>100 5 1432 1.495 (1.161–1.924) 1.472 (1.024–2.116) 39.6% 0.157    
<100 7 473 1.940 (1.132–3.325) 1.897 (0.922–3.902) 41.5% 0.115    

HR, hazard ratios; CI, confidence interval; Fixed, fixed-effects model; Random, random-effects model; *indicating heterogeneity.