Table 1.
Group | N | Age | Gender (M%:F%) | Braak stageb | MMSE | CAMCOG |
---|---|---|---|---|---|---|
Control | 20 | 79.2 ± 3.3 | 35:65 | 1.72 ± 0.32 | 28.8 ± 0.8 | na |
PSNDa | 21 | 85.0 ± 1.0 | 57:43 | 2.48 ± 0.25 | 27.2 ± 0.4 | 89.7 ± 1.3 |
PSDa | 20 | 87.3 ± 1.3 | 30:70 | 2.73 ± 0.24 | 15.9 ± 1.1 | 66.2 ± 2.5 |
VaD | 17 | 83.9 ± 1.6 | 41:59 | 1.93 ± 0.25 | 13.4 ± 3.7 | na |
Mixed | 18 | 84.5 ± 1.2 | 44:56 | 5.13 ± 0.22 | 10.6 ± 2.36 | na |
AD | 16 | 83.9 ± 1.9 | 56:44 | 5.31 ± 0.17 | 7.4 ± 1.9 | 39.1 ± 6.8 |
Numbers represent mean values (±SEM) and for the given number (N) of subjects. The causes of death included bronchopneumonia (95%), cardiac arrest, and carcinoma with no particular distribution in any group. The time period of postmortem interval between death and tissue retrieval ranged 39–47 hours for all the cases. There were no differences in the length of postmortem delay between groups.
Key: AD, Alzheimer's disease; CAMCOG, Cambridge cognition examination; F, female; M, male; MMSE, Mini–Mental State Examination; N, number; na, not available; NPD, no pathological diagnosis; PSD, poststroke demented; PSND, poststroke nondemented; SEM, standard error of the mean; VaD, vascular dementia.
Mean vascular pathology scores (range) for PSND and PSD groups were 13.5 (13–14) and 13.3 (9–17) compared to 8.1 (8–10) for controls (p < 0.05). These scores were derived as described previously (Deramecourt et al., 2012).
Braak staging scores were different in mixed and AD cases compared to all other groups (p < 0.05).