Table 2.
Hazard ratios (HR) for hip fracture by sex-specific hemoglobin decile Non-Hispanic white adults age 65+ years, NHANES III follow-up
| Sex-specific Hb percentile | Base model (Age, sex-adjusted) | Full multivariate model* | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| n cases | HR | LL | UL | HR | LL | UL | |
| Sex-specific hemoglobin decile | |||||||
| 1 | 25 | 2.96 | 1.44 | 6.08 | 2.24 | 1.09 | 4.63 |
| 2 | 19 | 1.56 | 0.95 | 2.55 | 1.54 | 0.97 | 2.46 |
| 3 | 19 | 1.79 | 0.90 | 3.57 | 1.40 | 0.62 | 3.14 |
| 4 | 17 | 1.66 | 0.71 | 3.88 | 1.74 | 0.74 | 4.06 |
| 5–6 (reference) | 27 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 |
| 7 | 16 | 1.54 | 0.71 | 3.36 | 1.60 | 0.71 | 3.61 |
| 8 | 19 | 2.16 | 0.95 | 4.91 | 2.01 | 0.82 | 4.98 |
| 9 | 19 | 2.53 | 1.28 | 5.00 | 2.44 | 1.21 | 4.90 |
| 10 | 22 | 2.06 | 1.09 | 3.92 | 2.37 | 1.35 | 4.16 |
| p=0.05** | p=0.008** | ||||||
*
adjusted for age, sex, ever smoked, femur neck BMD, iron/folate deficiency, inflammation, renal insufficiency, BMI, timed chair stand.
**
p value for the overall relationship between hemoglobin and hip fracture risk
LL=lower limit of 95% confidence interval; UL=upper limit of 95% confidence interval