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. Author manuscript; available in PMC: 2016 Feb 19.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2013 Jan 31;22(4):728–735. doi: 10.1158/1055-9965.EPI-12-1280

Table 1.

USPSTF increased-risk family history patterns (1)

Non-Ashkenazi Jewish Women:
  • 1

    Two first-degree relatives with breast cancer, 1 of whom received the diagnosis at age 50 years or younger

  • 2

    A combination of 3 or more first- or second-degree relatives with breast cancer regardless of age at diagnosis

  • 3

    A combination of both breast and ovarian cancer among first- and second-degree relatives

  • 4

    A first-degree relative with bilateral breast cancer

  • 5

    A combination of 2 or more first- or second-degree relatives with ovarian cancer regardless of age at diagnosis

  • 6

    A first- or second-degree relative with both breast and ovarian cancer at any age

  • 7

    A history of breast cancer in a male relative

Women of Ashkenazi Jewish Heritage:
  • 8

    Any first-degree relative (or 2 second-degree relatives on the same side of the family) with breast or ovarian cancer