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. 2016 Feb 19;6:21119. doi: 10.1038/srep21119

Figure 3.

Figure 3

(A) Clinical scores of infant Swiss Webster mice inoculated with NVAV strain Te34 by the intraperitoneal route. Data are combined from two independent experiments, consisting of 10 mice each. Mice were monitored twice daily for disease severity. Clinical scores were designated as: 1, ruffled fur/hunched back; 2, hyperactivity/twitching; 3, paresis/difficulty walking; 4, paralysis; and 5, moribund/euthanized. Scores are shown for each mouse, beginning on day 16 post-inoculation. Error bars represent SEM. (B) Real-time RT-PCR quantification of NVAV RNA in lung, liver, kidney, spleen and brain of Swiss Webster mice inoculated with NVAV strain Te34. NVAV RNA copies per μg of total RNA are shown for moribund mice sacrificed on day 17 post-inoculation. The solid horizontal line for each tissue signifies the median for five moribund mice.