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. 2015 Dec 11;4(12):720–727. doi: 10.1002/psp4.12045

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© 2015 The Authors CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Mean tumor diameter time course in HT‐29 xenografted mice treated with sunitinib 40 mg/kg daily for 12 days (filled circles) or placebo (empty circles) in Experiment 1.