Figure 5. DNP-MR imaging of AFR produced by the reaction of Asc and Trolox radicals.

Typical X-band ESR spectra for the Trolox radical solution, 2500 mM Asc solution, and mixture of the Trolox radical solution and 1250 mM Asc solution. X-band ESR absorption spectra (a), and time variations in the signal intensities of the doublet spectrum (b). X-band ESR absorption (c) DNP spectra (d), and representative DNP-MR images (e) for the mixture of Trolox radical solution and 1250 mM Asc (red), and 100 μM ¹⁴N-CmP (blue) and 50 μM Oxo63 (green) solutions. The images were obtained in the same conditions as those of the CoQ₀-mediated AFR, except for, with accumulation number of 2.