Table 1.

Transmission dynamics based on separate groups (GLM analysis).

group no.	vaccine strain	challenge strain	β (day−1) (95% CI)	Var(β)	infectious period (day) (95% CI)	R (95% CI)	Var(R)
high vaccine dose
1	H5N1 R65	H5N1 R65	0	n.a.	1.25 (0.48–3.26)	0	n.a.
2	R65-P18	H5N1 R65	0.27 (0.04–1.90)	2.72	1.2 (0.5–2.89)	0.32 (0.04–2.74)	3.32
3	R65-P30	H5N1 R65	0.38 (0.05–2.69)	2.73	1	0.38 (0.05–2.69)	2.73
4	unvaccinated	H5N1 R65	∞a	n.a.	1.37 (0.60–3.17)	∞a	n.a.
low vaccine dose
5	H5N1 R65	H5N1 R65	∞a	n.a.	3.11 (0.77–12.58)	∞a	n.a.
6	R65-P30	H5N1 R65	0.11 (0.02–0.81)	2.72	2.17 (0.38–12.47)	0.25 (0.02–3.43)	6.02
7	H5N2	H5N1 R65	∞a	n.a.	2.58 (0.42–15.78)	∞a	n.a.
8	unvaccinated	H5N1 R65	1.66 (0.68–4.07)	1.23	0.91 (0.11–7.45)	1.51 (0.15–14.85)	3.88
9	t/T-P42	H5N1 t/T	0	n.a.	3.73 (2.43–5.72)	0	n.a.
10	H5N1 t/T	H5N1 t/T	0	n.a.	5.49 (2.78–10.88)	0	n.a.
11	unvaccinated	H5N1 t/T	∞a	n.a.	2.00 (0.41–9.66)	∞a	n.a.

^aAll contact animals were infected by day 2 p.i. leading to extreme β and R₀ values. n.a.: not applicable.