A sketch of the computational arterial model in the lumped element domain (b) and simulated arterial pressure and flow waveforms at the baseline model specifications representative of an adult with a body surface area of 1.5 m2 (a). The model consists of a one-dimensional (1D) large arterial segment, similar to an aorta, which is terminated with a three-element windkessel (WK3), representing the peripheral microcirculation. X is the normalized distance () from the inlet of the aorta to the major reflection site at the end of the aorta. Normalized time = tHR; in this particular simulation HR = 80 bpm. t, time; HR, heart rate; La, arterial inertance; Ca, arterial compliance; ZC, arterial characteristic impedance (); Cp, peripheral compliance; Rp, peripheral resistance. (Online version in colour.)