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. 2016 Feb 19;6:21239. doi: 10.1038/srep21239

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(a) MDA/Luc metastasis in the lung measured by luciferase activity (normalized by tissue weight). (b) Immunohistochemical (IHC) staining of human mitochondria in metastasis-affected lungs. (c) MDA/Luc metastasis in the hind-leg bone measured by luciferase activity (normalized by tissue weight). (d) IHC staining of human mitochondria in affected hind-leg bones (decalcified). Statistical comparisons are Student’s t-test. For all experiments, N = 5 animals per condition. Error bars: SEM. (b,d) large images are at 10× magnification; insets: 20× magnification image of the blue-arrow indicated area. Scale bars: 100 μm.