Table 2.
Top 15 Intein-Containing Proteins in Archaea.
| Protein | Number of Inteins | COG (category) | Description: Full Name | Distribution |
|---|---|---|---|---|
| MCM | 116 | COG0417 (L) |
Replicative DNA helicase (P-loop NTPase) |
Crenarcheota, Euryarchaeota, Other Archaea |
| PolC/DP2 | 80 | COG1933 (L) | DNA polymerase II large subunit | Euryarchaeota, Other Archaea |
| PolB | 67 | COG0417 (L) | DNA polymerase II small subunit | Euryarchaeota, Other Archaea |
| RNR | 43 | COG0209 (F) | Ribonucleotide reductase | Crenarcheota, Euryarchaeota, Other Archaea |
| RFC-S | 36 | COG0470 (L) |
Replication factor C small subunit (P-loop NTPase) |
Euryarchaeota, Other Archaea |
| Top6B | 15 | COG1389 (L) | Type II DNA topoisomerase VI subunit B | Euryarchaeota, Other Archaea |
| aIF2 | 15 | COG0532 (J) | Translation initiation factor IF-2 subunit gamma (P-loop NTPase) | Euryarchaeota, Other Archaea |
| RNA Pol | 14 | COG0086 (K) | DNA-directed RNA polymerase | Euryarchaeota |
| V-ATPase subunit A | 12 | COG1155 (C) |
V-type ATP synthase subunit A (P-loop NTPase) |
Euryarchaeota, Other Archaea |
| TopA | 11 | COG0550 (L) | archaeal DNA type IA topoisomerase | Euryarchaeota |
| Ski2 | 11 | COG1204 (L) |
Ski2-like DEAD/DEAH box RNA helicases, superfamily II helicase (P-loop NTPase) |
Euryarchaeota |
| RtcB | 10 | COG1690 (J) | tRNA-splicing ligase | Crenarcheota, Euryarchaeota, Other Archaea |
| UDP-GlcDH | 10 | COG1004 (M) | UDP-glucose/GDP-mannose_dehydrogenase | Euryarchaeota |
| LonB | 10 | COG1067 (O) |
ATP-dependent protease LA (P-loop NTPase) |
Euryarchaeota |
| RadA | 9 | COG0468 (L) | Recombination protein (P-loop NTPase) | Crenarcheota, Euryarchaeota |