Table 1.
Alternative or Noncanonical Isoforms Specific to HER2+/ER−/PR− Breast Cancers
| UniProtID | Ensembl Transcript ID | gene symbol | protein name | chromosome | expression in HER2+/ER−/PR− BC data set |
|---|---|---|---|---|---|
| sp|O15511-2|ARPC5_HUMAN | ENST00000294742 | ARPC5 | actin-related protein 2/3 complex subunit 5 isoform 2 | 1 | down |
| sp|Q8TDJ6-3|DMXL2_HUMAN | ENST00000543779 | DMXL2 | DmX-like protein 2 isoform 3 | 15 | up |
| sp|Q16665-3|HIF1A_HUMAN | ENST00000539097 | HIF1A | hypoxia-inducible factor 1-alpha isoform 3 | 14 | up |
| sp|Q07866-2|KLC1_HUMAN | ENST00000389744 | KLC1 | isoform C of kinesin light chain 1 | 14 | up |
| sp|Q86UP2-2|KTN1_HUMAN | ENST00000438792 | KTN1 | kinectin isoform 2 | 14 | down |
| sp|Q9UIQ6-2|LCAP_HUMAN | ENST00000395770 | LNPEP | leucyl-cystinyl aminopeptidase isoform 2 | 5 | up |
| sp|Q96G74-5|OTUD5_HUMAN | ENST00000376488 | OTUD5 | OTU domain-containing protein 5 isoform 5 | X | down |
| sp|Q96M27-3|PRRC1_HUMAN | ENST00000512635 | PRRC1 | protein PRRC1 isoform 3 | 5 | down |
| sp|Q6R327-3|RICTR_HUMAN | ENST00000296782 | RICTOR | rapamycin-insensitive companion of mTOR isoform 3 | 5 | up |
| sp|Q9NWF9-1|RN216_HUMAN | ENST00000389902 | RNF216 | E3 ubiquitin-protein ligase RNF216 isoform 2 | 7 | up |
| sp|Q8N0Y2-2|ZN444_HUMAN | ENST00000592949 | ZNF444 | zinc finger protein 444 isoform 2 | 19 | up |