FIGURE 2.

Mutation frequency of VB1–8 and V-cSμ alleles in wt or repair factor–deficient backgrounds. (A) Mutation frequency of VB1–8 allele in wt (n = 4), Ung^−/− (n = 5), Msh2^−/− (n = 3), and DKO (n = 4) mice (see details in Supplemental Table I). (B) Mutation frequency of the V-cSμ allele in wt (n = 5), Ung^−/− (n = 3), Msh2^−/− (n = 3), and DKO (n = 4) mice (see details in Supplemental Table II). (C) Statistical significance was calculated with a Student t test between different genetic backgrounds (two tailed, two samples with equal variance).