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. 2016 Jan 25;196(5):2335–2347. doi: 10.4049/jimmunol.1502184

FIGURE 3.

FIGURE 3.

Frequency of deletions and insertions (indels) of VB1–8 and V-cSμ alleles. (A) Frequency of indels in VB1–8 allele in wt (n = 4), Ung−/− (n = 5), Msh2−/− (n = 3), and DKO (n = 4) mice (see details in Supplemental Table I). (B) The frequency of indels in the V-cSμ allele in wt (n = 5), Ung−/− (n = 3), Msh2−/− (n = 3), and DKO (n = 4) mice (see details in Supplemental Table II). (C) Statistical significance was calculated with a Student t test between different genetic backgrounds (two tailed, two samples with equal variance). (D) The percentage of indels that occurred in different regions of the KI cSμ sequence in V-cSμ/wt samples (n = 5). Data represent means ± SEM. (E) The percentage of indels that occurred in different regions of the KI cSμ sequence in V-cSμ/Msh2−/− samples (n = 3). Data represent means ± SEM. Nucleotide position in KI cSμ region: AGCT sparse region, 99–599 bp; intermediate region, 600–717 bp; dense region, 718–1065 bp.