Table I. Highly mutated nucleotides in the VB1–8 allele.

Base Pair Location	No. of Mutations	Base Pair	Location	AGCT
VB1–8/wt highly mutated nucleotides
596	33	C	D/J junction and CDR 3	Yes
478	26	G	CDR 2	No
595	22	G	D/J junction and CDR 3	Yes
592	20	G	D and CDR 3	No
373	15	G	CDR 1	Yes
809	14	C	JH2 intron	Yes
395	13	G	V exon	No
599	13	C	JH2 exon and CDR 3	No
451	12	G	CDR 2	No
374	11	G	CDR 1	Yes
897	11	G	After JH2 intron	Yes
594	10	A	D/J junction	Yes
479	9	C	CDR 2	No
584	9	C	D and CDR 3	No
311	8	G	V exon	Yes
458	8	G	CDR 2	No
589	8	G	D and CDR 3	No
338	7	G	V exon	Yes
379	7	G	CDR 1	No
918	7	G	After JH2 intron	No
VB1–8/DKO highly mutated nucleotides
596	95	C	D/J junction and CDR 3	Yes
373	67	G	CDR 1	Yes
809	64	C	JH2 intron	Yes
595	62	G	D/J junction and CDR 3	Yes
599	57	C	JH2 and CDR 3	No
383	55	G	CDR 1	No
478	55	G	CDR 2	No
897	48	G	After JH2 intron	Yes
374	44	G	CDR 1	Yes
675	44	C	JH2 intron	Yes
395	43	G	V exon	No
592	37	G	D and CDR 3	No
898	37	C	After JH2 intron	Yes
312	36	C	V exon	Yes
512	35	C	V exon	No
293	34	G	V exon	No
527	34	G	V exon	Yes
674	33	G	JH2 intron	Yes
339	32	C	V exon	Yes
504	32	C	V exon	No