Table 1.
Univariate analysis |
Multivariate analysis |
||||
---|---|---|---|---|---|
139 triple-negative breast cancer patients | DS-survival HR [95% CI] | p value | DS-survival HR [95% CI] | p value | |
Menopausal status | Pre | 1 | |||
Post | 1.56 [0.95–2.55] | 0.08 | |||
Tumor size (mm) | <20 mm | 1 | |||
>20 mm | 1.03 [0.58–1.82] | 0.92 | |||
Tumor grade | II | 1 | |||
III | 1.23 [0.45–3.39] | 0.69 | |||
Lymph node status | 0 | 1 | |||
1 | 0.84 [0.42–1.65] | 0.61 | |||
NPI score | <5.4 | 1 | 1 | ||
>5.4 | 2.15 [1.28–3.60] | 0.003 | 2.30 [1.36–3.89] | 0.002 | |
Cellularity | Low | 1 | |||
Moderate | 0.57 [0.22–1.46] | 0.24 | |||
High | 0.59 [0.25–1.39] | 0.23 | |||
P53 status | Wild-type | 1 | |||
Mutant | 2.42 [1.15–5.09] | 0.02 | |||
Immunity1 metagene expression | High | 1 | |||
Low | 0.97 [0.60–1.58] | 0.91 | |||
Immunity2 metagene expression | High | 1 | 1 | ||
Low | 2.59 [1.54–4.34] | 0.0002 | 2.68 [1.59–4.52] | 0.0002 | |
Proliferation/DNA damage metagene expression | High | 1 | |||
Low | 1.13 [0.69–1.84] | 0.63 | |||
AR-like metagene expression | High | 1 | |||
Moderate | 1.07 [0.59–1.94] | 0.82 | |||
Low | 0.98 [0.50–1.94] | 0.96 | |||
Matrix/Invasion1 metagene expression | High | 1 | |||
Low | 1.23 [0.76–2.01] | 0.40 | |||
Matrix2 metagene expression | High | 1 | |||
Low | 0.99 [0.61–1.61] | 0.96 |
Abbreviations: NPI, Nottingham Prognostic Index; AR, androgen receptor; HR, hazard ratio; CI, confidence interval.