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. 2016 Jan 26;4(2):e12692. doi: 10.14814/phy2.12692

Figure 1.

Figure 1

RGS2 deficiency increases impedance to uterine artery blood flow. (A) Representative uterine artery Doppler ultrasonography waveforms from nonpregnant wild‐type (Rgs2+/+), and Rgs2 heterozygous (Rgs2+/−) and homozygous knockout (Rgs2−/−) mice obtained under isoflurane anesthesia. Pulse wave velocities were acquired at an angle of 30° and frequency of 24 Hz. (B) Uterine artery waveforms from Rgs2+/+ (n = 7), Rgs2+/− (n = 7) and Rgs2−/− (n = 9) were analyzed to obtain peak systolic velocity (PSV or V max), least diastolic velocity (LDV or V min), and mean velocity (MV or V mean), which were used to derive resistive index, pulsatile index, and PSV‐to‐LDV ratio for each genotype. Values are mean ± SE. *,**P < 0.05, 0.01 versus Rgs2+/+.