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Effect of tetrodotoxin on cellular functions of cultured fibroblasts. Fibroblasts were cultivated with normal culture medium (control) or medium supplemented with 10 μmol/L tetrodotoxin (TTX). Proliferation (A; SR, n = 7; AF, n = 7), migration (B; SR, n = 7; AF, n = 4) and differentiation (C; SR, n = 5; AF, n = 3) were assessed as described in Figure 2. *P < 0.05, unpaired Student's t‐test.
