Table 3.
Potassium and sodium current parameters
| SR | AF | P | |
|---|---|---|---|
| IK parameters | |||
| ss inactivation V0.5, mV | −23.0 ± 1.9 | −28.6 ± 1.8 | 0.053 |
| K | 11.3 ± 1.9 | 8.4 ± 0.7 | 0.104 |
| Noninactivating fraction % | 51.9 ± 3.7 | 43.6 ± 4.5 | 0.213 |
| n | 9/5 | 15/5 | – |
| INa parameters | |||
| Activation V0.5, mV | −27.8 ± 2.2 | −29.9 ± 1.2 | 0.363 |
| K | 3.2 ± 0.3 | 3.1 ± 0.2 | 0.806 |
| n | 11/6 | 20/7 | – |
| ss inactivation V0.5, mV | −63.2 ± 3.6 | −64.7 ± 1.7 | 0.372 |
| K | 7.8 ± 1.3 | 6.9 ± 0.4 | 0.338 |
| n | 5/3 | 16/6 | – |
Voltage for half maximum activation and/or steady‐state (ss) inactivation (V0.5) and the respective slope factors (k) were obtained from fitting a Boltzmann function (see Material and Methods) to the data points shown in Figure 5D and Figure 6F. Data were compared using a two‐tailed unpaired Student's t test.