Table 1.
Normal Na+ diet Day 3 | Low Na+ diet Day 3 | High Na+ diet Day 3 | Post Ang‐II Day 14 | |||||
---|---|---|---|---|---|---|---|---|
Control | KO | Control | KO | Control | KO | Control | KO | |
Food intake (g) | 4.7 ± 0.2 | 4.4 ± 0.2 | 4.5 ± 0.5 | 4.2 ± 0.3 | 4.6 ± 0.3 | 5.2 ± 0.3 | 5.4 ± 0.3 | 4.9 ± 0.1 |
Water intake (mL) | 3.8 ± 0.5 | 3.8 ± 0.1 | 3.6 ± 0.5 | 3.1 ± 0.2 | 6.1 ± 0.4 | 6.2 ± 0.7 | 5.6 ± 0.3 | 3.9 ± 0.2 |
Weight (g) | 34.3 ± 4.3 | 36.8 ± 2.8 | 33.0 ± 2.8 | 35.7 ± 2.8 | 32.8 ± 3.7 | 35.5 ± 3.7 | 32.1 ± 1.5 | 33.1 ± 0.9 |
Urine volume (mL/day) | 1.5 ± 0.2 | 1.2 ± 0.1 | 1.1 ± 0.2 | 0.9 ± 0.2 | 3.0 ± 0.2 | 3.5 ± 0.4 | 3.4 ± 0.6 | 2.2 ± 0.2 |
Urine Na+ excretion (μeq/day) | 252 ± 31 | 248 ± 20 | 33 ± 4 | 38 ± 7 | 1819 ± 160 | 2002 ± 168 | 446 ± 50 | 358 ± 39 |