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Glomerular filtration rate (GFR, panel A) and urine flow rate (panel B) prior to and during acute Ang II infusion (5.0 ng/kg/min) for 1 h in anesthetized male and female SHR. Data are mean ± SEM; n = 7–8 rats in each group. *P < 0.05 versus female SHR; ≠P < 0.05 versus baseline.
