Table 1.

Average data of basal and menthol treatment of different metabolic parameters

	Wfs1KO	WT
Weight (g)	18.38 ± 2.50	27.85 ± 3.47c
Weight change (Δg)	0.22 ± 2.44	−0.25 ± 1.33
Food consumption (g)	1.48 ± 1.03	2.54 ± 0.94c
Food consumption (Δg)	0.2 ± 0.34	0.24 ± 0.58
Water consumption (mL)	1.76 ± 2.21	2.59 ± 1.58a
Water consumption (ΔmL)	−0.38 ± 0.23	0.36 ± 0.18
Body temperature (°C)	35.76 ± 2.24	36.86 ± 1.25a
Body temperature change after 1 h menthol administration (Δ°C)	0.57 ± 2.24	0.65 ± 1.25
Body temperature change after 2 h menthol administration (Δ°C)	0.68 ± 2.24	0.77 ± 1.25
O2 consumption (mL/h/kg)	7290 ± 1816c	5435 ± 1108
CO2 production (mL/h/kg)	6827 ± 2177b	5516 ± 1352
Heat production (kcal/h/kg)	36.07 ± 9.79c	27.47 ± 5.78
Respiratory coefficient 3 h after menthol administration	0.89	0.89
Respiratory coefficient 7 h after menthol administration	0.92	0.87
Respiratory coefficient 12 h after menthol administration	0.96	0.92
Respiratory coefficient 14 h after menthol administration	0.97	0.94

Data are expressed as mean values ± SD.

^a P < 0.05.

^b P < 0.005.

^c P < 0.001.