Fig. 3.

Effect of CIH on sensory nerve response of the carotid body to hypoxia in WT and Cacna1h^−/− mice. A: representative examples of carotid body (CB) sensory nerve responses [impulses per second (imp/s)] to hypoxia (Po₂ ∼35 mmHg) in WT and Cacna1h^−/− mice exposed to either normoxia or CIH. Horizontal bars represent the duration of the hypoxic challenge. Inset: superimposed action potentials of a “single” fiber from which data were derived. B: average data (means ± SE) of carotid body sensory nerve response to hypoxia presented as stimulus-evoked activity minus baseline activity (Δimp/s). Each bar represents the data from 10–16 carotid bodies. **P < 0.01; n.s., not significant (P > 0.05).