Table 3. Haplotype effects for DTX1 (rs2384077-rs10744794).
| Haplotype | Frequency | Case, Control Frequencies | p(χ2 test) | Adjusted pa | Corrected pb |
|---|---|---|---|---|---|
| Infants | |||||
| AT | 0.79 | 0.839, 0.740 | 2.58E-05 | 4.14E-05 | 3.73E-04 |
| GC | 0.138 | 0.101, 0.177 | 1.00E-04 | 6.24E-03 | 0.0562 |
| AC | 0.065 | 0.060, 0.071 | 0.4436 | 0.2564 | 1 |
| Adults | |||||
| AT | 0.747 | 0.826, 0.691 | 0.0011 | 2.30E-02 | 0.207 |
| GC | 0.166 | 0.110, 0.206 | 0.0063 | 4.10E-03 | 0.0369 |
| AC | 0.075 | 0.064, 0.083 | 0.4489 | 0.5722 | 1 |
| Combined | |||||
| AT | 0.778 | 0.836, 0.725 | 5.62E-08 | 3.67E-06 | 3.30E-05 |
| GC | 0.146 | 0.103, 0.186 | 1.72E-06 | 5.33E-06 | 4.80E-05 |
| AC | 0.068 | 0.061, 0.074 | 0.2697 | 0.5632 | 1 |
a: p-values adjusted for age, gender, BMI, and smoking status (adults) using logistic regression.
b: p-values corrected by Bonferroni correction.