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. 2016 Feb 19;11(2):e0149656. doi: 10.1371/journal.pone.0149656

Fig 5. Pimaradienoic acid (PA) inhibited carrageenan-induced superoxide anion production.

Fig 5

Mice were treated per oral (p.o.) with PA (10 mg/kg) or vehicle (DMSO 2% diluted in saline) 30 minutes before the intraperitoneal (i.p.) injection of carrageenan (500 μg/cavity). (A) Superoxide anion production and (B) NBT reaction positive cells (presence of formazan crystals) were determined in peritoneal cavity exudates 3 hours after carrageenan injection. Results are means ± SEM of six mice per group per experiment, and are representative of two separate experiments. [*p< 0.05 compared with the saline group, and #p< 0.05 compared to the vehicle group (One-way ANOVA followed by Tukey’s test)].