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. 2016 Feb 19;11(2):e0149783. doi: 10.1371/journal.pone.0149783

Fig 4. IL-17 axis deficiency augments hepatic steatosis, but protects from hepatocellular damage.

Fig 4

8 week old male IL-17RA-/-, IL-17A-/-, and IL-17F-/- mice on a C57BL/6 background and WT controls (n = 4-8/condition) were placed on MCDD or chow diet for 4 weeks. (A) Hepatic triglyceride levels. (B) Hepatic SCD-1 mRNA expression. (C) Serum alanine transaminase (ALT) levels. AU = Arbitrary units, as compared to beta actin. Data represent means + SE; a representative of two separate experiments. Student t test *P < 0.05, ** P < 0.01, *** P < 0.001.