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. Author manuscript; available in PMC: 2016 Feb 19.
Published in final edited form as: Ann Surg. 2012 Jan;255(1):109–115. doi: 10.1097/SLA.0b013e318238f461

Table 2.

Univariate Analysis of Clinicopathologic Factors Predictive of Non-SLN Metastases

Characteristic Odds Ratio 95% CI P-value

Age (per year) 1.002 0.985–1.019 .83

Pathologic tumor size (cm) (per unit) 1.199 1.074–1.337 .001

Histology .03
 IDC Reference -
 ILC 1.731 0.905–3.310
 mixed IDC/ILC 0.513 0.265–0.994
 other 0.420 0.092–1.923

Grade .53
 I Reference -
 II 1.317 0.655–2.645
 III 1.496 0.730–3.067

Multifocal disease .28
 yes 1.312 0.799–2.154
 no Reference -

ER .65
 positive 1.138 0.655–1.978
 negative Reference -

PR .15
 positive 0.744 0.497–1.114
 negative Reference -

HER2 .64
 positive 1.123 0.694–1.817
 negative Reference -

LVI .02
 present 1.594 1.080–2.353
 absent Reference

Number of SLN identified 0.765 0.666–0.879 <.001

Number of positive SLN 1.706 1.323–2.200 <.001

SLN maximum metastasis size (mm) 1.186 1.129–1.246 <.001

Extranodal extension <.001
 present 3.388 2.195–5.230
 absent Reference -

Abbreviations: CI, confidence interval; IDC, invasive ductal carcinoma; ILC, invasive lobular carcinoma; ER, estrogen receptor ; PR, progesterone receptor, HER2, HER2/neu ; LVI, lymphovascular invasion ; SLN, sentinel lymph node