Table 4. Reliability metrics for language laterality in controls, HGG patients and LGG patients.
LIe and LIm represent the laterality index characterized by the extent of activated brain volume, and the sum of brain map signal intensity, respectively. The Pearson correlation coefficients, r, are reported with their respective confidence interval (CI) in brackets.
| Rhyming Task | ||||
| Metric | Patients (n = 12) | Controls (n = 12) | HGG (n = 6) | LGG (n = 6) |
| % of subjects with reproducible laterality across LIe, LIm, ts, ts-, and ts+ | 91.7% [75,100] | 100% | 83.3% [50,100] | 100% |
| % of subjects with reproducible laterality across LIe, ts, ts-, and ts+ | 91.7% [75,100] | 100% | 83.3% [50,100] | 100% |
| % of subjects with reproducible laterality across LIm, ts, ts-, and ts+ | 100% | 100% | 100% | 100% |
| Group Pearson correlation coefficient (LIe at ts) | r = 0.34 [-0.29,0.76] | r = 0.91 [0.72,0.98] | r = 0.11 [-0.77,0.84] | r = 0.55 [-0.47,0.94] |
| Group Pearson correlation coefficient (LIm at ts) | r = -0.03 [-0.59,0.56] | r = 0.90 [0.68,0.97] | r = 0.38 [-0.62,0.91] | r = 0.11 [-0.77,0.85] |
| Phonemic Fluency Task | ||||
| Metric | Patients (n = 12) | Controls (n = 12) | HGG (n = 6) | LGG (n = 6) |
| % of subjects with reproducible laterality across LIe, LIm, ts, ts-, and ts+ | 91.7% [75,100] | 66.7% [41.7,91.7] | 83.3% [50,100] | 100% |
| % of subjects with reproducible laterality across LIe, ts, ts-, and ts+ | 91.7% [75,100] | 66.7% [41.7,91.7] | 83.3% [50,100] | 100% |
| % of subjects with reproducible laterality across LIm, ts, ts-, and ts+ | 91.7% [75,100] | 75.0% [50,100] | 83.3% [50,100] | 100% |
| Group Pearson correlation coefficient (LIe at ts) | r = 0.72 [0.24,0.91] | r = 0.63 [0.08,0.88] | r = 0.73 [-0.20,0.97] | r = 0.05 [-0.79,0.83] |
| Group Pearson correlation coefficient (LIm at ts) | r = 0.69 [0.19,0.91] | r = 0.66 [0.14,0.90] | r = 0.72 [-0.22,0.97] | r = 0.50 [-0.52,0.93] |