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Known NEMO C-terminus mutations and inflammatory disease phenotypes
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The predicted protein sequences of C-terminus NEMO mutations, which result from missense mutation, nonsense mutation, or frame-shift mutation are depicted. The proline-rich sequence and zinc finger domains are depicted by yellow and green shading, respectively. Mutations associated with inflammatory disease are bounded by a red box. Amino acid residues, which differ from wild-type NEMO, are shown in boldface.
