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. 2016 Jan 21;113(6):1606–1611. doi: 10.1073/pnas.1517562113

Fig. 2.

Fig. 2.

The resistance to Jo2-induced apoptosis is tissue-specific phenotype in MSM. (A) Thymocytes from both B6 and MSM/Ms are susceptible to Jo2-mediated lethality. Thymocytes were cultured in triplicate plus Jo2 plus protein G (PG) plus zVAD for 8 h, and an ATP assay for viability was carried out for the various stimulations at the end of the assay. (B) Susceptibility of C57BL6 or MSM/Ms thymocytes to membrane-bound FasL (mFasL). (C) Susceptibility of peritoneal macrophages to Jo2. (D) MEFs from MSM/Ms and B6 are susceptible to Jo2. For A–D, the viability was measured using the ATP assay (CelltiterGlo), and survival was made relative to values from the untreated group (media only). All data are representative of three independent experiments.