. Author manuscript; available in PMC: 2016 May 18.

Published in final edited form as: Mol Psychiatry. 2015 Sep 1;21(3):357–363. doi: 10.1038/mp.2015.134

Table 3.

Hierarchical Linear Regression Analysis of Genetic and Epigenetic Variation at SKA2 and Current PTSD Symptom Severity

	Model 1	Model 2	Model 3

	β (SE)	β (SE)	β (SE)
Step 1
Age	−.10 (0.3)	−.10 (0.3)	−.10 (0.3)
Sex	.04 (7.3)	.04 (7.3)	.04 (7.3)
Ancestry PC1	.02 (29.9)	.02 (29.9)	.02 (29.9)
Ancestry PC2	.08 (30.1)	.08 (30.1)	.08 (30.1)
Ancestry PC3	−.16 (30.1)^*	−.16 (30.1)^*	−.16 (30.1)^*
Step 2
rs7208505 Genotype	−.16 (2.9)^*	--------	−.16 (2.9)^*
cg13989295 Methylation	--------	−.07 (0.4)	--------
Step 3
cg13989295 Methylation (methylation_adj)	--------	--------	.37 (0.9)^*

Note. N = 199. PC = principal component.

Model 1. Step1: R²= .043, Step2: Δ R²= .024*.

Model 2. Step1: R²= .043, Step2: Δ R²= .01.

Model 3. Step1: R²= .043, Step2: Δ R²= .024*, Step3: Δ R²= .026*.

p <.05.