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. Author manuscript; available in PMC: 2017 Mar 1.
Published in final edited form as: Br J Surg. 2016 Jan 21;103(4):366–373. doi: 10.1002/bjs.10055

Table 5.

Multivariable Analysis of Factors Associated with the Time from Injury to First Infection

Risk Factor Multivariable Hazard Ratio (95 per cent CI) P value
Any traumatic amputation 1.64 (1.39 – 1.96) <0.001
Admission to the ICUa
 LRMC only 1.60 (1.12 – 2.30) 0.011
 U.S. MTF ± LRMC 2.73 (1.99 – 3.74) <0.001
PRBC transfusions within 24 hours of injuryb
 ≥ 10 units 1.64 (1.35 – 1.98) <0.001
Tranexamic acid use 1.16 (0.98 – 1.38) 0.078

CI – confidence interval; ICU – intensive care unit; LRMC – Landstuhl Regional Medical Center; MTFs – military treatment facilities; PRBC – packed red blood cells plus whole blood

a

The reference value was non-ICU.

b

The reference was transfusion of <10 units.