Figure 3. MCP-2 × P-Tau181 interaction on FA (cool) and MD (warm).
Higher CSF MCP-1 and Higher P-Tau181 were associated with higher FA in right post central gyrus white matter, right anterior corona radiata, left internal capsule and with higher MD in the left precuneus. Results were corrected for non-stationarity using a random field theory based approach with a voxel level threshold of p<0.005 and a cluster level threshold of p<0.05. Blue clusters indicate FA results, while orange clusters indicate MD results. Variations in color map correspond to the size of the t-statistic. Results are overlaid on a T1-weighted image for anatomical detail. Right=Left.