Table 2. Mean and standard deviation NAA/tCr and % Gray Matter (GM) data for the left/right pons (L1 –L6; R1 –R6) and cerebellum (C1 –C4) voxels selected from the CSI matrix for analysis.

Significant changes are underlined for the NAA/tCr ratio between controls and marked with ‘☆’ for low fatigue or ‘★’ for high fatigue voxels (p < 0.05). No significant differences were observed for NAA/tCr, or for %GM, in voxels in the pons (white) or in the cerebellum (light gray).

Controls				Low Fatigue				High Fatigue
% GM				% GM				% GM
R6	R5	L5	L6	R6	R5	L5	L6	R6	R5	L5	L6
12.3 ± 5.7	14.3 ± 6.6	13.1 ± 6.8	12.4 ± 4.9	11.2 ± 10.4	16.2 ± 10.7	16.7 ± 10.3	16.0 ± 13.0	11.0 ± 5.4	11.3 ± 4.1	11.8 ± 4.6	12.3 ± 5.1
R4	R3	L3	L4	R4	R3	L3	L4	R4	R3	L3	L4
31.3 ± 7.8	34.9 ± 7.0	34.3 ± 9.1	36.5 ± 10.3	35.2 ± 9.4	34.8 ± 13.3	31.7 ± 12.0	39.5 ± 12.2	29.3 ± 8.4	32.5 ± 6.3	30.9 ± 9.7	28.8 ± 6.0
R2	R1	L1	L2	R2	R1	L1	L2	R2	R1	L1	L2
62.6 ± 8.9	63.6 ± 9.1	60.3 ± 8.7	67.2 ± 11.2	62.3 ± 14.5	62.6 ± 11.8	60.0 ± 10.1	63.5 ± 11.3	59.9 ± 8.1	60.1 ± 6.2	57.3 ± 8.8	65.8 ± 6.9
C1	C2	C3	C4	C1	C2	C3	C4	C1	C2	C3	C4
90.0 ± 8.3	94.3 ± 4.0	93.9 ± 5.2	90.7 ± 7.8	92.2 ± 4.4	94.7 ± 4.6	94.1 ± 4.6	89.6 ± 7.4	81.9 ± 14.5	89.8 ± 7.7	87.9 ± 8.8	83.3 ± 11.9
NAA / tCr				NAA / tCr				NAA / tCr
R6 ★	R5 ★	L5	L6 ☆	R6	R5	L5	L6 ☆	R6 ★	R5 ★	L5	L6
2.55 ± 0.50	2.84 ± 0.56	2.69 ± 0.53	2.52 ± 0.54	2.53 ± 0.51	2.71 ± 0.32	2.50 ± 0.55	1.91 ± 0.34	2.12 ± 0.29	2.32 ± 0.49	2.36 ± 0.50	2.32 ± 0.47
R4	R3	L3	L4 ★	R4	R3	L3	L4	R4	R3	L3	L4 ★
2.09 ± 0.40	2.39 ± 0.51	2.38 ± 0.45	2.11 ± 0.47	2.01 ± 0.26	2.22 ± 0.32	2.07 ± 0.46	1.72 ± 0.44	1.82 ± 0.31	2.14 ± 0.50	2.35 ± 0.38	1.91 ± 0.29
R2	R1	L1	L2	R2	R1	L1	L2	R2	R1	L1	L2
1.48 ± 0.24	1.72 ± 0.33	1.72 ± 0.33	1.43 ± 0.23	1.40 ± 0.09	1.63 ± 0.26	1.66 ± 0.23	1.37 ± 0.20	1.44 ± 0.22	1.74 ± 0.26	1.80 ± 0.26	1.54 ± 0.19
C1	C2	C3	C4	C1	C2	C3	C4	C1	C2	C3	C4
1.20 ± 0.17	1.23 ± 0.17	1.20 ± 0.17	1.12 ± 0.16	1.29 ± 0.23	1.32 ± 0.26	1.29 ± 0.22	1.17 ± 0.19	1.19 ± 0.20	1.28 ± 0.27	1.24 ± 0.20	1.12 ± 0.17