Table 3. G6PD diagnostic tests analyzed in 610 subjects living in Panenggo Ede village, Southwest Sumba, tested against G6PD gold standard test.
| Cut off | Performance indicator 1 | Male | P-value | Female | P-value | ||
|---|---|---|---|---|---|---|---|
| RDT 2 | FST 3 | RDT | FST | ||||
| 10% | Sensitivity | 100.0 (80.5–100) | 88.2 (63.6–98.5) | 0.48 | 100.0 (29.2–100) | 100.0 (29.2–100) | 1.0 |
| Specificity | 95.9 (92.6–98.0) | 89.7 (85.2–93.2) | 0.01 | 92.2 (88.9–94.8) | 91.4 (87.9–94.1) | 0.78 | |
| DPV | 63.0 (42.4–80.6) | 37.5 (22.7–54.2) | 0.05 | 10.0 (2.1–26.5) | 9.1 (1.9–24.3) | 1.0 | |
| NPV | 100.0 (98.4–100) | 99.1 (96.8–99.9) | 0.23 | 100.0 (98.9–100) | 100.0 (98.8–100) | 1.0 | |
| 30% | Sensitivity | 100.0 (85.8–100) | 91.7 (73–99) | 0.49 | 83.3 (35.9–99.6) | 100.0 (54.1–100) | 1.0 |
| Specificity | 98.7 (96.3–99.7) | 92.4 (88.2–95.4) | 0.001 | 92.7 (89.5–95.2) | 92.2 (88.8–94.8) | 0.89 | |
| DPV | 88.9 (70.8–97.6) | 55.0 (38.5–70.7) | 0.004 | 16.7 (5.6–34.7) | 18.2 (7–35.5) | 1.0 | |
| NPV | 100.0 (98.4–100) | 99.1 (96.8–99.9) | 0.24 | 99.7 (98.3–100) | 100.0 (98.8–100) | 1.0 | |
| 60% | Sensitivity | 96.0 (79.6–99.9) | 88.0 (68.8–97.5) | 0.61 | 44.0 (24.4–65.1) | 60.0 (38.7–78.9) | 0.39 |
| Specificity | 98.7 (96.3–99.7) | 92.3 (88.2–95.4) | 0.001 | 94.2 (91–96.4) | 94.5 (91.4–96.7) | 1.0 | |
| DPV | 88.9 (70.8–97.6) | 55.0 (38.5–70.7) | 0.004 | 36.7 (19.9–56.1) | 45.5 (28.1–63.6) | 0.61 | |
| NPV | 99.6 (97.6–100) | 98.6 (96.1–99.7) | 0.36 | 95.6 (92.8–97.6) | 96.8 (94.3–98.5) | 0.53 | |
1 Proportion and 95% confidence interval.
2 CareStart RDT (Access Bio) and tested in field setting with temperature 28–34°C and humidity between 55–76%.
3 FST (Trinity Biotech) and tested in field laboratory with temperature 26–29°C.