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The effects of aging on the gene expression were analyzed by 2-way ANOVA (*P <0.05 vs. OLETF rats at 21 weeks of age). The effects of rosiglitazone on the metabolic genes in each fat depot were evaluated among the different groups at 21 weeks (†P <0.05 vs. the same deposit in OLETF rats at 21 weeks; RGZ, rosiglitazone treated).
