Table 2. Comparison of metabolic parameters measured in rats with aging or PPARγ agonist treatment.

	LETO rats	OLETF rats
	21 weeks (n = 4)	21 weeks (n = 8)	31 weeks (n = 8)	43 weeks (n = 5)	21 weeks PPARγ agonist (n = 8)
Body weight (g)	463.3±14.7 *	586.6±11.0	614.2±19.2	620.0±40.0	608.9±38.3
Subcutaneous fat (% body weight)	0.7±0.1 *	2.6±0.7	4.8±0.3*	4.7±0.8*	3.2±0.3
Visceral fat (% body weight)	0.8±0.1 *	3.3±0.5	11.0±1.2*	12.9 ±1.2*	2.4±0.5*
V/S ratio	1.1±0.1 *	1.3±0.1	2.3±0.1 *	2.8±0.4*	0.8±0.1 *
Glucose (mmol/l)	7.1±0.7*	11.6±0.4	12.1±0.3	16.9±0.1*	9.8±0.5 *
Insulin (ng/ml)	155.8±68.3*	511.8±75.7	566.0±356.6	708.6±383.4*	409.9±20.1*
Free fatty acid (mmol/l)	524.0±90.6 *	944.1±62.5	958.7±30.2	1053.3±51.5*	517.8±52.8 *
Triglyceride (mmol/l)	0.2±0.0*	1.6±0.3	2.3±0.6	2.0±0.2	0.3±0.0*

Data are summarized in mean ± SEM.

*P<0.05, compared with OLETF rats at 21 weeks.