Table 2. Performance of Genexpert for detection of RIF resistance: sensitivity and specificity of the genexpert for detection of RIF resistance in comparison with gold standard phenotypic [MGIT 960, LC-DST] and genotypic [sequencing] results.

		MTB drug resistance detection (Gold standard methods)
SAMPLES	MTB drug resistance detection by Xpert (n = 72)	Phenotypic method Culture-DST (MGIT960)		Genotypic method rpoB sequencing (RRDR)
PULMONARY SAMPLES		Resistant	Sensitive	Resistant	Sensitive
	Resistant	14	0	14	0
	Sensitive	2	56	1	57
	Sensitivity	87.5% [95%CI:61.65% to 98.45%]		93.33%[95%CI: 68.05% to 99.83%]
	Specificity	100%[95% CI: 93.62% to 100.00%]		100%[95% CI: 93.62% to 100.0%]
EXTRA-PULMONARY SAMPLES	MTB drug resistance detection by Xpert (n = 35)	Phenotypic method Culture-DST (MGIT960)		Genotypic method rpoB sequencing (RRDR)
		Resistant	Sensitive	Resistant	Sensitive
	Resistant	9	0	9	0
	Sensitive	2	24	1	25
	Sensitivity	81.82% [95%CI: 48.22% to 97.72%]		90% [95%CI: 55.50% to 98.75%]
	Specificity	100% [95%CI: 85.75% to 100.00%]		100% [95%CI: 86.28% to 100.00%]